Two distinct actin-binding sites of smooth muscle calponin
نویسندگان
چکیده
منابع مشابه
Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells.
Phorbol ester induces actin cytoskeleton rearrangements in cultured vascular smooth muscle cells. Calponin and SM22 alpha are major components of differentiated smooth muscle and potential regulators of actin cytoskeleton interactions. Here we show that actin fibers decorated with h1 CaP remain stable, whereas SM22 alpha-decorated actin bundles undergo rapid reorganization into podosomes within...
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There has been considerable controversy regarding the lineage relationship between smooth muscle cells (SMCs) and myofibroblasts, because they express a number of common cell-selective markers including smooth muscle (SM) alpha-actin. We have shown previously that MCAT elements within the SM alpha-actin promoter confer differential activity in cultured SMCs versus myofibroblasts. In the present...
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There has been considerable controversy regarding the lineage relationship between smooth muscle cells (SMCs) and myofibroblasts, because they express a number of common cell-selective markers including smooth muscle (SM) -actin. We have shown previously that MCAT elements within the SM -actin promoter confer differential activity in cultured SMCs versus myofibroblasts. In the present study, to...
متن کاملExpression of Smooth Muscle Calponin in Synovial Sarcoma
Purpose. Histogenesis of synovial sarcoma remains controversial and reliable molecular markers for diagnosis are necessary. Expression of basic calponin, a smooth muscle differentiation-specific actin-binding protein, was studied in synovial sarcoma.Subjects and Methods. The basic calponin gene and the gene product were analyzed by reverse transcription PCR analysis (RT-PCR) and immunohistochem...
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In the early 1980s, the oncogene field was in transition. The biological properties of more than 20 oncogenes had been described in animal tumor models and cell transformation assays. Attention was shifting to the question of how these genes actually function. In a few cases, it was obvious. The v-Sis protein (encoded by the transforming gene of simian sarcoma virus) was shown to be related to ...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1998
ISSN: 0014-2956,1432-1033
DOI: 10.1046/j.1432-1327.1998.2510262.x